If this is your first time using the ChipWhisperer toolchain, the easiest way to start is to use a virtual machine with everything already set up for you.
- Install the VMWare Player software (free). Note that this program is available for Windows and Linux - if you're running a Mac, you're out of luck.
- Download a ChipWhisperer virtual machine image release. The current latest release with a VM image is v0.11RC1.
- Unzip the VMWare image and open the file
ChipWhisperer Lubuntu 32-bit.vmdkin VMWare Player.
There's an old Youtube tutorial of this setup available online.